Karyology performed for one batch of crl 1730 in 1996 reflected a hypodiploid human cell line with a modal chromosome number of 45 occurring in 72 of the cells counted all of which had monosomic n13. Meaning they have been preserved after only 1 to 3 passages from the initial source material. General description human umbilical vein endothelial cells huvec provide a classic model system to study many aspects of endothelial function and disease such as normal abnormal and tumor associated angiogenesis oxidative stress hypoxia and inflammation related pathways in endothelia under normal and pathological conditions cardiovascular related complications associated with various.
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